Radioprotective effect of 5-azacytidine in AKR mice.
نویسندگان
چکیده
The administration of 5-azacytidine to mice (AKR strain) prior to irradiation with a supralethal dose of X-rays markedly reduces their mortality. In the pretreated animals the number of blood leukocytes and of bone marrow nucleated cells is considerably higher than in the animals that have been only irradiated. It is supposed that the radioprotective effect of 5-azacytidine favourably in fluences the proliferation of the stem-cells which are responsible for the repopulation of the bone marrow.
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ورودعنوان ژورنال:
- Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete
دوره 24 3 شماره
صفحات -
تاریخ انتشار 1969